Miss Munasinghage Silva

PhD, BSc (Honours)

Post Doctoral Fellow

About me

Miss Lakmali Silva finished her Bachelor and Honours degrees in Molecular Biology and Biotechnology at University of Peradeniya, Sri Lanka, where she won the University Award of Academic Excellence in Special Science 2009/10.

Then she moved to Australia to pursue her PhD in proteases in tumour microenvironment where she won prestigious scholarships, such as International Postgraduate Research Scholarship (IPRS), Australian Postgraduate Award (APA), and Institute of Health and Biomedical Innovation (IHBI) Top-Up scholarship in 2012 for her outstanding CV and research quality.

Since then she has been a PhD candidate in Distinguished professor Judith Clements AC lab at the Institute of Health and Biomedical Innovation, QUT, based at the Translational Research Institute on the Princess Alexandra Hospital Biomedical Precinct.

Her areas of expertise include ovarian cancer, with respect to the Kallikrein proteases and their utility as biomarkers and therapeutic targets for cancer progression, proteomics, transcriptomics and bioinformatics.

 

Projects

mechanistic role of a protease, KLK7 in the ovarian tumour microenvironment

Publications

Proteomics Clin Appl. 2014 Jun;8(5-6):403-15. doi: 10.1002/prca.201300098. Epub 2014 May 11.Proteomic and other analyses to determine the functional consequences of deregulated kallikrein-related peptidase (KLK) expression in prostate and ovarian cancer.Fuhrman-Luck RA, Silva ML, Dong Y, Irving-Rodgers H, Stoll T, Hastie ML, Loessner D, Gorman JJ, Clements JA

 

Biochimie. 2015 Sep 4. pii: S0300-9084(15)00277-1. doi: 10.1016/j.biochi.2015.09.002. [Epub ahead of print]The kallikrein-related peptidase family: Dysregulation and functions during cancer progression.Kryza T, Silva ML, Loessner D, Heuzé-Vourc'h N, Clements JA.

Research fields

Proteomics, Transcriptomics, Tumour_microenvironment, Bioinformatics, Ovarian Cancer