Dr Michelle M Hill

PhD, BSc (Hon I), BA

Head, Cancer Proteomics Group. ARC Future Fellow. Academic lead, TRI Proteomics Core Facility

Projects

About me

Dr Michelle Hill earned her PhD at the University of Queensland, Brisbane, Australia in 2000. After 3 postdoctoral positions, Dr Hill established the cancer proteomics group at the University of Queensland Diamantina Institute in 2009 with a Career Development Fellowship from the National Health and Medical Research Council. Her research group utilizes proteomics and systems analysis to investigate molecular mechanisms linking lipid raft dysfunction and cancer metastasis. Dr Hill’s group has also developed a novel high throughput glycoproteomics pipeline for cancer biomarker discovery, which they are utilizing to develop new blood tests for cancer. Dr Hill is on the organising committee of the Australiasian Proteomics Society and the Australasian Extracellular Vesicles Conference. She has received several prestigious awards, most recently the Australian Research Council Future Fellowship.

Publications

  1. Moon H, Lee CS, Inder KL, Sharma S, Choi E, Black DM, Lê Cao KA, Winterford C, Coward JI, Ling MT, the Australian Prostate Cancer BioResource, Craik DJ, Parton RG, Russell PJ, Hill MM. 2013 PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer. Oncogene. doi: 10.1038/onc.2013.315
  2. Shah AK, Saunders NA, Barbour AP, Hill MM. 2013 Early diagnostic biomarkers for esophageal adenocarcinoma - the current state of play. Cancer Epidemiology, Biomarkers & Prevention. 22:1185-1209.
  3. Inder KL, Davis MJ, Hill MM. 2013 Ripples in the pond – using a systems approach to decipher the cellular functions of membrane microdomains. Molecular BioSystems. Invited Review. 9(3):330–338.
  4. Nguyen HD, Wood IA and Hill MM. 2012 A robust permutation test for quantitative SILAC proteomics experiments. Journal of Integrated Omics. 2: DOI: 10.5584/jiomics.v2i2.109
  5. Inder KL, Zheng YZ, Loo D, Moon H, Nguyen H, Davis M, Clements J, Parton RG, Foster LJ, Hill MM. 2012 Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways. Mol Cell Proteomics. 11(2):M111.012245.
  6. Loo D, Mollee PN, Renaut P, Hill MM. 2011 Proteomics in Molecular Diagnosis: Typing of Amyloidosis. J Biomed Biotechnol. doi:10.1155/2011/754109.
  7. Loo D, Jones A, Hill MM. Lectin magnetic bead array for biomarker discovery. 2010.  J Proteome Res. 9:5496-500.
  8. Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VMJ, Martin S, Hancock JF and Parton RG. PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. 2008 Cell 132, 113-124.

Research fields

Cancer diagnostics, cancer metastasis, systems biology, cell biology,