Dr Yu-Chen Enya Chen

PhD, Bachelor Degree

Former PhD candidate

Projects

About me

Current Porject:

Activation of FcγR-dependent responses to therapeutic antibodies by Nurse Like cells requires PI3Kδ

 

Publications

Chen YCE, Mapp S, Blumenthal A, Burgess ML, Mollee P, Gill D, Saunders NA, The duality of macrophage function in chronic lymphocytic leukaemia. Biochim Biophys Acta Rev Cancer, 2017, 1868(1):176-182. IF = 7.4

Yu-Chen Enya Chen, Melinda Burgess, Sally Mapp, Peter Mollee, Devinder Gill, Antje Blumenthal, Nicholas A Saunders, PI3K-p110δ contributes to antibody responses by macrophages in chronic lymphocytic leukemia. Leukemia, 2020, 34:451-461. IF = 9.4

Yu-Chen Enya Chen, Melinda Burgess, Sally Mapp, Peter Mollee, Devinder Gill, Antje Blumenthal, Nicholas A Saunders, SIRPα suppresses response to therapeutic antibodies by nurse like cells from chronic lymphocytic leukemia patients. Leukemia, under review. IF = 9.4

Burgess M, Chen YCE, Mapp S, Mollee P, Gill D, Saunders NA, Identifying an obinutuzumab resistant subpopulation of monocyte-derived-macrophages from patients with CLL. Leuk Lymphoma, 2020. IF= 2.6

Burgess M, Chen YCE, Mapp S, Blumenthal A, Mollee P, Gill D, Saunders NA, HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients. Oncogene, 2020, 39:5756-5767. IF = 6.6

Supervision

Supervisor: Assoc. Prof. Nicholas Saunders

Research fields

Blood Cancer - Chronic Lymphocytic Leukemia