Dr Darsy Darssan
Ph.D. (Stats), M.App.Sc. (Stats & Oper. Res.), B.Sc. (Hons., Stats & Pure Maths)
Lecturer in Biostatistics
- T: 07 3365 5272
- E: [email protected]
Projects
Survival GWAS on prostate cancer patients.
This project has two components: The first component will be a statistical survival genome-wide association study (GWAS) of over 4000 prostate cancer patients with over 500 thousand single nucleotide polymorphisms (SNPs). This analysis will identify the SNPs which show statistically strong association with the prostate cancer.
The second component will be a post-GWAS analysis, a lab based experiments on the SNPs which were identified as strongly associated with prostate cancer in the statistical analysis. Results obtained from these post-GWAS analyses will highlight the potential of exploiting prostate cancer risk-associated germline variants to identify new gene networks and signalling pathways involved in prostate tumorigenesis.
This project is a collaboration between QUT and UQ at TRI. The first component will be conducted by Dr. Darsy Darssan at UQ School of Public Health. The second component will be conducted at Jyotsna’s lab at TRI by Dr. Srilakshmi Srinivasan.
About me
2019-Present: Lecturer in Biostatistics, The University of Queensland, Australia.
2015-2018: Biostatistician, The University of Queensland, Australia.
2014-2015: Postdoctoral researcher in Biostatistics, The University of Liverpool, UK.
2011-2014: Sessional academic, Queensland Univeristy of Technology, Australia.
2010-2013: Ph.D., Statistics, Queensland Univeristy of Technology, Australia.
2009-2010: Associate Research Fellow - Applied Statistics, Univeristy of Wollongong, Australia.
2008-2009: Statistician, Univeristy of New South Wales, Australia.
2007-2008: Data Analyst, Australian Council for Educational Research, Australia.
2006-2008: M.App.Sc, Statistics and Operational Research, RMIT University, Australia.
2001-2005: B.Sc. (Hons.), Statistics and Pure Mathematics, Univeristy of Jaffna, Sri Lanka.
Publications
Statistical Methods
Darssan, D, Thompson, MH, & Pettitt, AN (2014). Incorporating adverse event relatedness into dose‐finding clinical trial designs. Statistics in medicine, 33(7), 1146-1161
Biostatistics
Scarfe, L, Rak-Raszewska, A, Geraci, S, Darssan, D, Sharkey, J, Huang, J, & ... (2015). Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy. Scientific reports, 5, 13601
Medical Statistics
Zhang, Y, Darssan, D, Pascoe, EM, Johnson, DW, Pi, H, & Dong, J (2018). Vitamin D status and mortality risk among patients on dialysis: a systematic review and meta-analysis of observational studies. Nephrology Dialysis Transplantation
Roberts, MA, Darssan, D, Badve, SV, Carroll, RP, & ... (2017). Carvedilol and Cardiac Biomarkers in Dialysis Patients: Secondary Analysis of a Randomized Controlled Trial. Kidney and Blood Pressure Research, 42(6), 1033-1044
Menon, A, Gray, LC, Fatehi, F, Darssan, D, Bird, D, Bennetts, D, & Russell, AW (2017). A comparison of characteristics of patients seen in a tertiary hospital diabetes telehealth service versus specialist face-to-face outpatients. Journal of telemedicine and telecare, 23(10), 842-849
Htay, H, Cho, Y, Pascoe, EM, Darssan, D, Nadeau-Fredette, & ... (2017). Multicenter registry analysis of center characteristics associated with technique failure in patients on incident peritoneal dialysis. Clinical Journal of the American Society of Nephrology, CJN., 12321216
Htay, H, Cho, Y, Pascoe, EM, Darssan, D, Hawley, CM, & Johnson, DW (2016). Predictors of residual renal function decline in peritoneal dialysis patients: the balANZ trial. Peritoneal Dialysis International, pdi. 2016., 206
Htay, H, Cho, Y, Pascoe, EM, Darssan, D, Hawley, C, & ... (2017). Outcomes of Corynebacterium Peritonitis: A Multicenter Registry Analysis. Peritoneal Dialysis International, 37(6), 619-626
Htay, H, Cho, Y, Pascoe, EM, Darssan, D, Nadeau-Fredette, AC, & ... (2018). Center Effects and Peritoneal Dialysis Peritonitis Outcomes: Analysis of a National Registry. American Journal of Kidney Diseases, 71(6), 814-821
See, EJ, Johnson, DW, Hawley, CM, Pascoe, EM, Darssan, D, Clayton, PA, & ... (2017). Early Peritonitis and its outcome in incident peritoneal dialysis patients. Peritoneal Dialysis International, pdi. 2017., 29
Jegatheesan, D, Johnson, DW, Cho, Y, Pascoe, EM, Darssan, D, Htay, H, & ... (2018). The Relationship Between Body Mass Index and Organism-Specific Peritonitis. Peritoneal Dialysis International, 38(3), 206-214
Nataatmadja, M, Cho, Y, Pascoe, EM, Darssan, D, Hawley, CM, & Johnson, DW (2017). Association between peritoneal glucose exposure and peritonitis in peritoneal dialysis patients: the balANZ trial (vol 37, pg 407, 2017). PERITONEAL DIALYSIS INTERNATIONAL, 37(4), 486
Nataatmadja, M, Cho, Y, Pascoe, EM, Darssan, D, Hawley, CM, & Johnson, DW (2017). Association between peritoneal glucose exposure and peritonitis in peritoneal dialysis patients: the balANZ trial. Peritoneal Dialysis International, pdi. 2016., 263
Krishnasamy, R, ......, Darssan, D, Vergara, LA, Paul-Brent PA, &.... (2018). Design and methods of the REMOVAL-HD study: a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HaemoDialysis patients. BMC nephrology, 19(1), 89
Research fields
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