Burhan A. Khan

MSc. Microbiology & Immunology; BA. Biological Sciences

Projects

Publications

Selected

  • Bohn-Goldbaum E, Lee VY, Skinner SR, Frazer IH, Khan BA, Booy R, Edwards KM. Acute exercise does not improve response to HPV vaccination series in adolescents. Papillomavirus Res. (2019) [Epub ahead of print]
  • He L, Le KY, Khan BA, Nguyen TH, Hunt RL, Bae JS, Kabat J, Zheng Y, Cheung GY, Li M, Otto M. Resistance to leukocytes ties benefits of quorum-sensing dysfunctionality to biofilm infection. Nat Microbiol. 4:1114-1119 (2019).
  • Mukherjee P, Winkler CW, Taylor KG, Woods TA, Khan BA, Nair V, Peterson KE. SARM1, not MyD88, mediates TLR7/TLR9-induced apoptosis in neurons. J Immunol. 195(10):4913-21 (2015).
  • Khan BA, Yeh AJ, Cheung GY, Otto M. Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections. Expert Opin Investig Drugs. 24(5):689-704 (2015).
  • Cheung GY, Wang R, Khan BA, Sturdevant DE, Otto M. Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infect Immun. 79(5):1927-35 (2011).
  • Wang R*, Khan BA*, Cheung GY, Bach TH, Jameson-Lee M, Kong KF, Queck SY*, Otto M. Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest. 121(1):238-48 (2011). *indicates equal contribution to work
  • Queck SY, Khan BA, Wang R, Bach TH, Kretschmer D, Chen L, Kreiswirth BN, Peschel A, DeLeo FR, Otto M. Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. PLoS Pathog. 5(7):e1000533 (2009).
  • Villaruz AE, Bubeck-Wardenburg J, Khan BA, Whitney AR, Sturdevant DE, Gardner DJ, DeLeo FR, Otto M. A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Disease. 200(5):724-34 (2009).
  • Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M. RNAIII-independent target gene control by the agr quorum-sensing system: Insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell. 32(1):150-8 (2008).

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