Burhan Khan

M.S. Microbiology & Immunology (Tulane University School of Medicine) | B.A. Biological Sciences (Northwestern University)

Visiting Scholar

Projects

Publications

Mukherjee P, Winkler CW, Taylor KG, Woods TA, Khan BA, Nair V, Peterson KE. SARM1, not MyD88, mediates TLR7/TLR9-induced apoptosis in neurons. J Immunol. 195(10):4913-21 (2015).

Khan BA, Yeh AJ, Cheung GY, Otto M. Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections. Expert Opin Investig Drugs. 24(5):689-704 (2015).

Cheung GY, Wang R, Khan BA, Sturdevant DE, Otto M. Role of the accessory gene regulator agr in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. Infect Immun. 79(5):1927-35 (2011).

Wang R*, Khan BA*, Cheung GY, Bach TH, Jameson-Lee M, Kong KF, Queck SY*, Otto M. Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest. 121(1):238-48 (2011). *indicates equal contribution to work

Queck SY, Khan BA, Wang R, Bach TH, Kretschmer D, Chen L, Kreiswirth BN, Peschel A, DeLeo FR, Otto M. Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. PLoS Pathog. 5(7):e1000533 (2009).

Villaruz AE, Bubeck-Wardenburg J, Khan BA, Whitney AR, Sturdevant DE, Gardner DJ, DeLeo FR, Otto M. A point mutation in the agr locus rather than expression of the Panton-Valentine leukocidin caused previously reported phenotypes in Staphylococcus aureus pneumonia and gene regulation. J Infect Disease. 200(5):724-34 (2009).

Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M. RNAIII-independent target gene control by the agr quorum-sensing system: Insight into the evolution of virulence regulation in Staphylococcus aureus. Mol Cell. 32(1):150-8 (2008).