Alterations of the gastrointestinal barrier do not only play a critical role for inflammatory disorders of the gastrointestinal tract such as Crohn's disease, but also for the manifestation and progression of chronic liver disease such as Nonalcoholic Steatohepatitis (NASH) or functional gastrointestinal disorders such as IBS. Professor Gerald Holtmann and his team are conducting work to better characterise the altered barrier function and the links to mucosal inflammation and the gastrointestinal microbiome.

Key Researchers
Gerald Holtmann