OVERVIEW

Genomics

Genomic medicine research focuses on understanding the genetic causes of many common human diseases. Researchers at TRI are investigating how genomics can potentially be used to inform diagnosis, prognosis and treatment of diseases, including cancers. 

Genomics in disease - A wide range of genomics research is underway at TRI, including the use of genomics to identify targets for osteoporosis intervention, relationships between birthweight and cardiometabolic risk, and other diseases including rheumatology and ankylosing spondylitis.

  • An overview of genomics research from UQ's Frazer Institute, based at TRI, can be viewed here
  • The UQ Centre for Clinical Genomics, located at TRI, uses innovations in gene sequencing, genotyping and proteomic technologies to research a wide range of complex diseases, including cancer, arthritis, osteoporosis, diabetes, eczema and other chronic diseases.

Genomics diagnostic service - The QUT Australian Translational Genomics Centre (ATCG) is affiliated with TRI and based at the PA Hospital, as the first genomics diagnostic service in Queensland. The facility offers rapid and comprehensive screening for cancer mutations, identifying specific mutational profiles at diagnosis required to inform whether they are suitable for treatment with certain medications. Read more.  

Microbial biology and metagenomics - Professor Mark Morrison and his team are using DNA sequencing technologies to produce new insights into the microbiome. They aim to improve methods for monitoring and adjusting the gut microbiota to improve and maintain health, and better diagnose and treat disease. Read more

Key Researchers
 
Matthew Arthur Brown
Peter M Visscher
Suyinn Chong
David Evans
Geoffrey Faulkner
Mark Morrison
Mitchell Stark
Nicole Warrington
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GENOMICS RESEARCH PROGRAMS
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Cancer Genomics
Osteoporosis and Bone Disease
Article
International Clinical Trials Day: Q and A with TRI’s Steve Turner On International Clinical Trials Day on 20 May, we honour the incredibly hardworking professionals in the clinical trials...Read more
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Better patient outcomes the focus of new LINC grants Translational Research Institute (TRI), Metro South Health (MSH) and Mater Research, have announced the recipients of almost $400,000 in new...Read more
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COVID-19 does not integrate into our DNA TRI-based scientists from Mater Research Institute-UQ, in collaboration with The University of Queenland’s Queensland Brain Institute , have shown that...Read more
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More education on the benefits of genetic testing could accelerate its potential A study of Queensland health consumers has found most have relatively low levels of understanding and awareness of...Read more
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Researchers discover no single gene governs left-handedness In the largest study of its kind to date, TRI-based University of Queensland (UQ) researchers have identified 48 genetic variants that...Read more
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Genome a treasure trove for new disease treatments and diagnostics Queensland scientist Dr Mark Adams is uncovering potential new treatment targets and diagnostics for a range of diseases, including...Read more
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World first genetic and environmental risks identified for common form of childhood epilepsy A new study of childhood epilepsy has identified maternal smoking in pregnancy as an important risk factor...Read more
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QUT and UQ researchers based at TRI are part of team looking to improve health outcomes among Aboriginal and Torres Strait Islander communities by better understanding genetic association with...Read more
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Over $5.9 million in NHMRC funding awarded to TRI-based researchers for 2019 In the latest round of NHMRC funding announced this month, TRI-based researchers from UQ, QUT and Mater-UQ have secured...Read more

Identifying cancer-causing genetic mutations

Identifying cancer-causing genetic mutations

Professor Matt Brown is working to develop treatments, for cancer and immune-related diseases, based on a knowledge of genetic mutations and variants. 

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