Dr. Paraic O Cuiv
PhD (Microbiology and microbial genetics); BSc in Biotechnology
Head, Live Biotherapeutics at Microba
Projects
Publications
1. Ó Cuív, P., Klaassens, E. S., Smith, W. J., Mondot, S., Durkin, A. S., Harkins, D. M., Foster, L., McCorrison, J., Torralba, M., Nelson, K. E. and Morrison, M. (2014) Enterococcus faecium PC4.1, the draft genome sequence of a clade B strain isolated from human faeces. Genome Announcements, 2(1): e00022-14.
2. Ó Cuív, P., Gupta, R., Goswami, H. P. and Morrison, M. (2013) Extending the cellulosome paradigm: The modular Clostridium thermocellum cellulosomal serpin, PinA, is a broad spectrum inhibitor of subtilisin like proteases. Applied and Environmental Microbiology, 79(19): 6173-6175.3. Zhang, L., Morrison, M., Ó Cuív, P. and Rickard, C. M. (2013) Genome sequence of Stenotrophomonas maltophilia strain AU12-09, isolated from intravascular catheter. Genome Announcements, 1(3):e00195-13.
4. Ó Cuív, P., Klaassens, E. S., Smith, W. J., Mondot, S., Durkin, A. S., Harkins, D. M., Foster, L., McCorrison, J., Torralba, M., Nelson, K. E. and Morrison, M. (2013) The draft genome sequence of Enterococcus faecalis PC1.1, a candidate probiotic strain isolated from human faeces. Genome Announcements, 1(1):e00160-12.
5. Rosewarne, C. P., Cheung, J. L., Smith, W. J. M., Evans, P. N., Tomkins, N. W., Denman, S. E., Ó Cuív, P. and Morrison, M. (2012) Draft genome sequence of Treponema sp. Strain JC4, a novel spirochete isolated from the bovine rumen. Journal of Bacteriology 194(15): 4130.6. Zhang, L., Morrison, M., Ó Cuív, P. and Rickard, C. M. (2012) Genome sequence of Staphylococcus epidermidis strain AU12-03, isolated from an intravascular catheter. Journal of Bacteriology, 194(23): 6639.
7. Ó Cuív, P., Klaassens, E. S., Durkin, A. S., Harkins, D. M., Foster, L., McCorrison, J., Torralba, M., Nelson, K. E. and Morrison, M. (2011) Draft genome sequence of Bacteroides vulgatus PC510, a strain isolated from human faeces. Journal of Bacteriology, 193(15): 4025-4026. 8. Aguirre de Cárcer, D., Ó Cuív, P., Wang, T., Kang, S., Worthley, D., Whitehall, V., Gordon, I., McSweeney, C., Leggett, B. and Morrison, M. (2011) Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon. ISME Journal, 5(5):801-809.
9. Ó Cuív, P., Klaassens, E. S., Durkin, A. S., Harkins, D. M., Foster, L., McCorrison, J., Torralba, M., Nelson, K. E. and Morrison, M. (2011) Draft genome sequence of Turicibacter sanguinis PC909 isolated from human faeces. Journal of Bacteriology, 193(5):1288-1289.10. Ó Cuív, P., Aguirre de Cárcer, D., Jones, M., Klaassens, E. S., Worthley, D. L., Whitehall, V. L. J., Kang, S., McSweeney, C., Leggett, B. & Morrison, M. (2011) The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue. Microbial Ecology, 61(2):353-362.
11. Rosewarne, C. P., Pope, P. B., Denman, S. E., McSweeney, C. S., Ó Cuív, P. and Morrison, M. (2011) High-yield and phylogenetically robust methods of DNA recovery for analysis of microbial biofilms adherent to plant biomass in the herbivore gut. Microbial Ecology, 61(2):448-454.12. Ó Cuív, P., Keogh, D., Clarke, P., O'Connell, M. (2008) The hmuUV genes of Sinorhizobium meliloti 2011 encode the permease and ATPase components of an ABC transport system for the utilization of both haem and the hydroxamate siderophores, ferrichrome and ferrioxamine B. Molecular Microbiology, 70(5): 1261-73.
13. Kilbane, Z., Vaas, P. R., Ó Cuív, P. and O’Connor, B. (2007) Cloning and heterologous expression of bovine pyroglutamyl peptidase type-1 in Escherichia coli: purification, biochemical and kinetic characterisation. Molecular and Cellular Biochemistry, 297(1-2): 189-197.
14. Ó Cuív, P., Keogh, D., Clarke, P. and O’Connell, M. (2007) FoxB of Pseudomonas aeruginosa functions in the utilisation of the xenosiderophores ferrichrome, ferrioxamine B and schizokinen: evidence for transport redundancy at the inner membrane. Journal of Bacteriology, 189(1): 284-287.
15. Ó Cuív, P., Clarke, P. and O’Connell, M. (2006) Identification and characterisation of an iron regulated gene, chtA, required for the utilisation of the xenosiderophores aerobactin, rhizobactin 1021 and schizokinen by Pseudomonas aeruginosa. Microbiology, 152(4): 945-954.
16. Clarke, P., Ó Cuív, P. and O’Connell, M. (2005) Novel mobilizable prokaryotic two-hybrid system vectors for high-throughput protein interaction mapping in Escherichia coli by bacterial conjugation. Nucleic Acids Research, 33(2): e18.
17. Viguier C, Ó Cuív, P., Clarke P, and O'Connell M. (2005) RirA is the iron response regulator of the rhizobactin 1021 biosynthesis and transport genes in Sinorhizobium meliloti 2011. FEMS Microbiology Letters, 246(2): 235-242.
18. Ó Cuív, P., Clarke, P., Lynch, D. and O’Connell, M. (2004) Identification of rhtX and fptX, novel genes encoding proteins that show homology and function in the utilisation of the siderophores rhizobactin 1021 by Sinorhizobium meliloti and pyochelin by Pseudomonas aeruginosa, respectively. Journal of Bacteriology, 186(10): 2996-3005.
19. Lynch, D., O’Brien, J., Welch, T., Clarke, P., Ó Cuív, P., Crosa, J. H. and O’Connell, M. (2001) Genetic organisation of the region encoding regulation, biosynthesis and uptake of rhizobactin 1021, a siderophore produced by Sinorhizobium meliloti. Journal of Bacteriology, 183(8): 2576-2585.
